Relationship of physical activity and cognitive function to sleep quality in older adults with cognitive impairment:a mediating effect of resting EEG
MA Xiaochen
LI Shufan
JIA Shuqi
LIU Cong
ZHANG Zhenyu
HAN Dongyang
Abstract：Objective To investigate the relationship of physical activity(PA)and cognitive function to sleep quality in older adults with cognitive impairment based on resting electroencephalogram(EEG),and to explore the mediating role of specific EEG markers in the relationship between PA and sleep quality.
Methods From March to May,2024,137 older adults were recruited from Chenfu Jiayuan and Qiangwei Jiuli in Songji-ang district,and Luyan communities in Jinshan district,Shanghai.The assessments included Montreal Cognitive Assessment(MoCA),International Physical Activity Questionnaire-Short Form(IPAQ-SF)and Pittsburgh Sleep Quality Index(PSQI),along with a five-minute EEG recording.
Results There was significant difference in sleep quality among older adults with different levels of cognitive impair-ment(t=-7.400,P<0.001).The PSQI total score was negatively correlated with MoCA scores(r=-0.412,P<0.001)and total physical activity level(PAL)(r=-0.363,P<0.001).The θ power in the frontal areas(F3,F4)was significantly correlated with both PSQI scores and PAL(P<0.01).The θ power in F3+F4 exhibited a sig-nificant partial(effect size=-0.0004,95%CI-0.0007 to-0.0002)mediating effect between PA and sleep quali-ty in older adults with cognitive impairment.
Conclusion Older adults with more severe cognitive impairment tend to have poorer sleep quality,whereas higher PAL is associated with better sleep quality.PA can indirectly influence sleep quality in older adults with cognitive im-pairment by affecting θ power(F3+F4).
Keywords：physical activitysleep qualitycognitive impairmentolder adultselectroencephalography
Publication Date：2024-12-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：10( 1442-1451 )