Advance in Riluzole for Spinal Cord Injury (review)
WU Qi-chao
ZHANG Yan
ZHANG Wen-xiu
ZHANG Yan-jun
LIU Ya-dong
ZHAO Ying-lun
LIU Zong-jian
CHEN Xue-ming
Abstract：Spinal cord injury (SCI) is a disabling disease usually caused by trauma. The treatment and nursing of SCI patients has brought great economic burden to the society. This article introduced the mechanism of riluzole in treating spinal cord in-jury, including blocking Na+channels, reducing glutamate-mediated excitotoxicity, promoting the expression of neuro-trophic factors, and alleviating cellular oxidative stress damage and apoptosis, and the research progress on clinical trials of riluzole.
Keywords：spinal cord injuryriluzoleneuroprotectionamyotrophic lateral sclerosisreview
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 650-653 )