Research Related to Neural Protection of Hypoxic and Hyperoxic Preconditioning after Spinal Cord Injury (review)
ZHANG Wen- xiu
ZHANG Yan
ZHANG Yan- jun
WU Qi- chao
LIU Ya- dong
LIU Zong- jian
GUAN Yun
CHEN Xue-ming
Abstract：Repeated acute intermittent hypoxia promotes the expression of growth factors and neurotrophic factors, as well as the key molecules for neural protection and plasticity. Hypoxic preconditioning may improve the survival rate of transplant-ed stem cells and protect the neural function. Meanwhile, acute intermittent hypoxia can be an approach to improve re-spiratory function after spinal cord injury. Hyperbaric oxygen may improve the neural tolerance to hypoxia and isch-emia, to protect the structure of cells and tissues, and promote the neuranagenesis. It is important to study the role of hy-poxic and hyperoxic preconditioning in spinal cord injury.
Keywords：spinal cord injurypreconditioninghypoxiahyperoxiavascular endothelial growth factorhypoxia induc-ible factor-1stem cellsreview
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 90-92 )