Advance in Pathogenesis of Amyotrophic Lateral Sclerosis (review)
Abstract：Amyotrophic lateral sclerosis (ALS), including the familial and the sporadic, accounts for the most proportion of motor neu-ron disease. The pathogenesis of ALS covers gene mutation, oxidative stress, excitotoxicity, mitochondrial dysfunction, immune and inflam-matory, and so on. With interplay and interrelation, these mechanisms, finally, caused multisystem lesion especially motor neural system.
Keywords：amyotrophic lateral sclerosispathogenesis mechanismgene mutationoxidative stressexcitotoxicitymitochondrial dys-functionimmune and inflammatoryreview
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 685-689 )