Experimental Research Progress of Wnt Signaling Pathway in Spinal Cord Injury Repair (review)
MAN Xia-nan
CHEN Jian-er
Abstract：Wnt signaling pathway is one of the important signal transduction systems that involved in regulating nervous system devel-opment, which plays an important role in axonal regeneration, neural stem cell proliferation and differentiation into neurons and inhibition of differentiation into glial cells. After spinal cord injury, multiple Wnt protein expresses around the injury site, and some proteins of the Wnt family play an important role in spinal cord injury repair, in which the activation of Wnt/β-catenin signaling pathway is necessary for spinal cord regeneration after spinal cord injury.
Keywords：Wnt signaling pathwayspinal cord injuryneural stem cellsWnt/β-catenin pathwayreview
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 645-648 )