Role of Microglia in Damage after Ischemic Stroke (review)
WANG Dong
HOU Bo-ru
YANG Wen-zhen
KANG Jun-lin
REN Hai-jun
Abstract：Microglial cells are the resident immune cells of brain. The activated microglia produces a range of deleterious substances, which plays an important role in the inflammation of post-stroke, such as superoxide, nitric oxide, matrix metalloproteinases, etc. The activa-tion of microglia may involve triggering receptor expressed on myeloid cells-1, Toll-like receptors 4, peroxisome proliferator-activated re-ceptors, purinergic receptors, etc. Intervention targeted to microglial receptor is becoming a new strategy for ischemic stroke.
Keywords：ischemic strokemicrogliainjuryreceptorsreview
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 42-45 )