Effects of Lateral Gastrocnemius Muscle Branch Nerve Transferring on Deep Peroneal Nerve Impairment in Rats
LI Jun
LIU Chang-bin
DONG Xue-chao
GUO Yun
TANG Li
DU Liang-jie
GAO Feng
LIU Hong-wei
YANG De-gang
WANG Chong
LI Jian-jun
Abstract：Objective To explore the feasibility and effectiveness of lateral gastrocnemius muscle branch nerve transferring for deep pe-roneal nerve injury. Methods Thirty-two adult female Sprague-Dawley rats were divided into control group (n=8), sham group (n=8), nerve direct repairing group (n=8) and nerve transferring group (n=8). Twelve weeks after the anastomosis, the nerve anastomosis was observed vi-sually, the length of lateral of gastrocnemius muscle branch (L1), the diameter at the point of entering muscle (D1), the maximum detachable length of nervus peroneus communis (L2), the diameter of deep peroneal nerve (D2) and the distance between branch point and neck of fibu-la (S) were measured. The peroneal nerve functional index (PFI), the amplitude of compound muscle action potential (CMAP), nerve con-duction velocity (NCV), the weight of the tibialis anterior and the creatine kinase (CK) activity of theanterior tibial were compared among groups. Results L1<S was found in all the rats, indicating that the proximal tibial nerve muscular branches could not directly anastomose with the deep peroneal nerve in the neck of fibula without tension. The PFI, amplitude of CAMP, NCV, weight of the tibialis anterior and CK activity all improved in the nerve transferring group compared with those in the control group (P<0.05), and were not different from the nerve direct repairing group (P>0.05). Conclusion It is feasible that lateral head muscular branches of gastrocnemius nerve transferring can repair deep peroneal nerve injury, which is needed to separate superficial peroneal nerve and deep peroneal nerve in the epineurium without damaging nerve for tension free neuroanastomosis. Lateral head muscular branches of gastrocnemius nerve transferring can repair the func-tion after deep peroneal nerve injury.
Keywords：deep peroneal nerve injurytibial nerve muscular branchesnerve transferrepairrats
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 779-783 )