Resting-state Network of Brain in Leukoaraiosis Patients:A Magnetic Resonance Imaging Study
WEI Na
YAN Hao
BAI Li-jun
YAO Jing-fan
LI Yue-xiu
CHEN Hong-yan
ZHANG Yu-mei
Abstract：Objective To explore the diversity of resting-state network of brain between the patients with leukoaraiosis and the healthy people. Methods 31 patients with leukoaraiosis (patients) and 27 healthy persons (controls) were checked with resting-state functional mag-netic resonance imaging (rs-fMRI), and analyzed with the independent component analysis (ICA) to explore the resting-state functional brain network. Results The resting-state brain network was found in both the patients and the controls, which was coincident with the previ-ous studies. The active areas were the same in both groups, and the activation was weaken in the patients than in the controls, especially in quadrate gyri, posterior cingulate cortex, superior temporal gyrus, superior parietal gyrus, anterior central gyrus, post central gyrus, insula and prefrontal cortex. Conclusion There is a significant diversity of resting-state network of brain between the patients with leukoaraiosis and healthy people in the activation of active areas.
Keywords：leukoaraiosisresting-state networkdefault mode networkfunctional magnetic resonance imagingindependent compo-nent analysis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 793-798 )