Expression of Tumor Necrosis Factor-αand Interleukin-6 in Invasive Pituitary Adenoma
WU Jian-long
QIAO Jian-yong
DUAN Qing-hua
Abstract：Objective To study the tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6) expressed in invasive pituitary adenomas (IPA). Methods The expression of TNF-α and IL-6 were observed with immunohistochemstry (SP approach) in tissue from 40 cases of non-invasive pituitary adenomas (NIPA) and 40 cases of IPA. Results The expression of both TNF-αand IL-6 was significantly increased in the IPA tissues compared with those of NIPA (P<0.05). Conclusion TNF-αand IL-6 may play a role in the occurrence and development of IPA.
Keywords：invasive pituitary adenomatumor necrosis factor-αinterleukin-6
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 432-435 )