Effect of Electroacupuncture on Regional Cerebral Blood Flow in Patients with Post-stroke Depression
LI Jue-bao
YE Xiang-ming
CHENG Rui-dong
ZHU Gen-ying
YANG Ting
Abstract：Objective To explore the therapeutic effects of electroacupuncture on regional cerebral blood flow (rCBF) in patients with post-stroke depression. Methods 21 patients with post-stroke depression were randomly divided into electroacupuncture group (n=11) and drug group (n=10). The electroacupuncture group received electroacupuncture on double Hegu (LI4) and Taichong (LR3) once a day for 8 weeks, while the drug group took fluoxetine hydrochloride dispersible tablets 20 mg a day for 8 weeks. They were evaluated with Hamilton Self-rating Scale for Depression (HAMD) before, and 2 weeks, 4 weeks and 8 weeks after treatment respectively. The rCBF were measured with single positron emission computerized tomography (SPECT) before and 8 weeks after treatment. Results The score of HAMD de-creased more in the electroacupuncture group than in the drug group 2 weeks after treatment (P<0.05), and there was no significant differ-ence between the two groups 4 and 8 weeks after treatment (P>0.05). The rCBF was significantly greater in the electroacupuncture group than in the drug group. Conclusion That electroacupuncture is effective on post-stroke depression, which may be related with the increase of the rCBF levels.
Keywords：post-stroke depressionelectroacupunctureregional cerebral blood flowsingle photon emission computed tomography
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 192-195 )