Effect of Botulinum Toxin Type A on Spastic Hamstring in Children with Cerebral Palsy
Abstract：Objective To observe the effect of Botulinum toxin type A (BTX-A) injection on spastic hamstring in the children with cere-bral palsy. Methods 39 cerebral palsy children with spastic hamstring were divided into control group (n=20) and experimental group (n=19). The control group accepted physical therapy, while the experimental group accepted BTX-A injection in affected hamstring in addition. They were assessed with modified Ashworth Scale (MAS), Gross Motor Fucntion Measure (GMFM-88) and flexion angle of knee joints be-fore and after treatment. Results The scores of MAS and GMFM-88, and flexion angle of knee joints improved significantly 6 weeks after treatment in the experimental group (P<0.05), and improved more than that in the control group (P<0.05). Only the score of GMFM-88 im-proved significantly in the control group (P<0.05). Conclusion BTX-A injection can relieve hamstring spasticity in children with cerebral palsy, which may be helpful to correct abnormal gait and improve the motor function.
Keywords：cerebral palsyspasticityhamstringBotulinum toxin type Agait analysisgross motor fucntion
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 417-419 )