Predictive value of standardized lactic acid load for acute kidney injury after hip fracture surgery in the elderly
Zhang Kai
Jin Ping
Liu Yang
Zheng Qihui
Abstract：Objective To investigate the predictive value of standardized lactic acid load on acute kidney injury(AKI)after hip fracture surgery in the elderly.Methods A total of 100 elderly patients with hip fracture who underwent surgical treatment in our hospital from August 2023 to August 2025 were retrospectively included.Based on the occurrence of postoperative AKI,the patients were categorized into an AKI group comprising 26 cases and a non-AKI group with 74 cases.The general data,operation-related indicators and secondary outcome indicators of patients were collected.Logistic regression,both univariate and multivariate,was employed to assess the risk factors associated with postoperative AKI.The predictive performance of standardized lactic acid load for postoperative AKI was evaluated using the receiver operating characteristic(ROC)curve,and the secondary outcomes were compared according to the optimal cut-off value.Results Univariate analysis showed that preoperative Barthel index and albumin(ALB)level in AKI group were lower than those in non-AKI group,while serum creatinine(Scr)level and standardized lactic acid load were higher than those in non-AKI group(P<0.05).The multivariate Logistic regression analysis revealed that both preoperative Scr levels and standardized lactic acid load were independent risk factors for postoperative AKI.ROC curve analysis showed that the AUC of standardized lactate load for predicting postoperative AKI was 0.842,and the optimal cut-off value was 6.85 mmol·h/L,with a sensitivity of 60.0%and a specificity of 96.7%.Further grouping according to the cut-off value,the length of postoperative hospital stay,incidence of complications within 30 days and mortality in the high standardized lactate load group(n=32)were higher than those in the low standardized lactate load group(n=68)(P<0.05).Conclusions In elderly patients suffering from hip fracture,standardized lactate load emerges as a risk factor for postoperative AKI.It has a high predictive efficacy for postoperative AKI and can indicate postoperative adverse outcomes.It can be used as an important indicator for early clinical screening of high-risk patients.
Keywords：Elderly hip fractureAcute kidney injuryStandardized lactic acid loadPredictive value
Publication Date：2026-03-10
Online Publishing Date：2026-03-27(First online date of this platform, not the publication date of the document)
Pages：5( 213-217 )