Mechanisms of liver dysfunction in intracerebral hemorrhage
Zhou Shiya
Chen Xiaoguang
Abstract：Liver dysfunction is a common complication in patients with intracerebral hemorrhage(ICH)and can significantly affect prognosis.This article systematically reviews current research on ICH complicated by liver injury,summarizes the pathophysiological mechanisms through which ICH leads to liver dysfunction,and focuses on the potential mechanisms including neuroendocrine stress response,systemic inflammatory response,hepatic hypoperfusion,impaired drug metabolism,gut-liver axis dysfunction,brain-liver axis interactions,and genetic susceptibility.The aim is to provide a reference for comprehensive clinical management and future research.
Keywords：Intracerebral hemorrhageLiver dysfunctionSystemic inflammatory responseGut-Liver axisNeuroendocrine stress response
Publication Date：2026-02-10
Online Publishing Date：2026-03-18(First online date of this platform, not the publication date of the document)
Pages：3( 148-150 )