Consensus for blood purification therapy based on pharmacokinetics in acute poisoning from commonly used clinical drugs
Expert group on the consensus for blood purification therapy based on pharmacokinetics in acute poisoning from commonly used clinical drugs
Pan Longfei
Ma Qingbian
Zhu Huadong
Zhang Guoqiang
Ma Yuefeng
Pei Honghong
Abstract：The incidence of acute poisoning caused by commonly used clinical drugs has been increasing annually,but specific antidotes are lacking in most drug poisonings.Blood purification plays a crucial role in the treatment of acute poisoning.However,there are currently no unified recommendations in China regarding its application in cases of acute poisoning from commonly used clinical drugs.This consensus focuses on pharmacokinetics,summarizing and outlining the strategies for applying blood purification in the treatment of acute poisoning caused by these drugs.Its aim is to assist the clinicians in improving their understanding of pharmacokinetic parameters and the corresponding blood purification methods,so that they can select the appropriate blood purification technique and make suitable treatment plans based on the pharmacokinetic characteristics of the drug involved in order to improve the outcomes in treating the patients with acute poisoning from commonly used clinical drugs.
Keywords：PoisoningDrug overdosePharmacokineticsContinuous renal replacement therapyAcute poisoningDrug poisoningBlood purification
Publication Date：2024-11-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：10( 928-937 )