New progress in emergency treatment of acute pancreatitis
Chen Sanyang
Zhu Changju
Abstract：Acute pancreatitis(AP)is one of the most common causes of acute abdominal pain,and is divided into mild acute pancreatitis(MAP),moderate to severe acute pancreatitis(MSAP),and severe acute pancreatitis(SAP).The incidence of SAP is about 25％,and the condition is more severe at this time,often accompanied by multiple organ dysfunction,with a mortality rate as high as 30％.The etiology of AP in China is mainly biliary,high-fat and alcoholic,and its pathogenesis mainly includes abnormal activation of trypsinogen,pathological Ca ion(Ca2+)signaling,mitochondrial dysfunction,etc.The current treatment for AP mainly includes comprehensive internal medicine treatments such as fluid replacement and anti-inflammation,as well as minimally invasive treatments such as endoscopy and puncture.Compared with traditional surgical treatment,new treatment methods such as ascending ladder therapy have significant advantages in recent years.In summary,fully understanding the relevant risk factors and pathogenesis of AP patients,applying different methods to evaluate the severity of patients,and adopting appropriate treatment methods can significantly improve patient prognosis.
Keywords：Acute pancreatitisEtiologyPathogenesisTreatmentExosomeAscending ladder therapy
Publication Date：2024-10-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 903-907 )