The effect of early gastrointestinal decompression on the respiratory mechanics of the patients with mechanical ventilation after tracheal intubation
Ren Jiale
Wang Zhiwei
Zhang Wei
Yang Jianzhong
Abstract：Objective To explore the effect of early gastrointestinal decompression after tracheal intubation on the respiratory mechanics of mechanically ventilated patients and its clinical application value.Methods In this prospective observational study,132 mechanically ventilated patients who underwent tracheal intubation in emergency rescue of the First Affiliated Hospital of Xinjiang Medical University from March 2023 to June 2023 were divided into observation group(n =66)and control group(n =66).The observation group underwent gastrointestinal decompression within 1 hour after tracheal intubation,while the control group did not undergo gastrointestinal decompression 6 hours after tracheal intubation.General information was collected for both groups,and the changes in respiratory mechanics parameters,PaO2/FiO2,and intra-abdominal pressure(IAP)were monitored and analyzed at various time points:tracheal intubation(T0),1 hour of mechanical ventilation(T1),2 hours of mechanical ventilation(T2),4 hours of mechanical ventilation(T3),and 6 hours of mechanical ventilation(T4).Results At T0,there were no statistically significant differences in respiratory mechanics between the two groups(P>0.05);The peak airway pressure(Ppeak)decreased in both groups,but there was no statistically significant difference(P>0.05);At T3 and T4,the plateau pressure(Pplat)and mean airway pressure(Pmean)were significantly lower and the static lung compliance(Cstat)was significantly higher in the observation group compared to the control group(P<0.05);After T1,the PaO2/FiO2 of the observation group was significantly higher than that of the control group;At T4,the IAP of the observation group was significantly lower than that of the control group(P<0.05).Conclusions The gastrointestinal decompression within 1 hour after tracheal intubation is an effective method to improve respiratory mechanics,reduce IAP,and improve lung compliance and oxygenation for mechanically ventilated patients.
Keywords：Tracheal intubationEarly gastrointestinal decompressionPlateau pressureMean airway pressurePeak airway pressureStatic lung complianceIntra-abdominal pressureOxygenation
Publication Date：2024-01-10
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 88-92 )