Glycocalyx and its role during hemorrhagic shock
Zhao Meng
Zhao Zi-Gang
Abstract:The glycocalyx is an important component of endothelial double barrier, has various physiological functions includes anti-inflammation and anti-coagulation, etc. Hemorrhagic shock induces the damage of glycocalyx,which plays important roles in the vascular hyper-permeability, excessive inflammation, and increased blood coagulation, and becomes one of mechanisms by which refractory hemorrhagic shock. The current article reviews the structure and function of glycocalyx and its role during hemorrhagic shock, thus, provides a novel approach for treatment of hemorrhagic shock basing on glycocalyx.
Keywords:GlycocalyxHemorrhagic shockCapillary leak syndrome(CLS)
Publication Date:2018-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:6( 273-278 )
