Influence of aevolar-artery partial pressure on patients with ARDS caused by lung infection
Yu Ynog-bo
Li Xing-hua
Wang Jing-jing
Wang Yong-qiang
Li Yin
Abstract：Objective To evaluate the effects of aveolar -artery partial pressure on ARDS patient′s ventilation weaning which was caused by lung infection .Methods A retrospective analysis of 64 cases who were diagnosed ARDS caused by lung infection and required mechanical ventilation were selected;all patients were admitted to the ICU from July 2015 to July 2017 in our hospital .According to whether patients can wean ventilation or not , we divided these patients into two groups , the successful weaning ventilation group and the failure weaning ventilation group .We observed age, gender, creatinine (Cr), blood ALT, blood AST, total bilirubin (TBil), oxygenation index and aveolar -artery partial pressure ( PA-a DO2 ) value of the two groups before mechanical ventilatory , and we also compared the two group′s oxygenation index and P A-a DO2 values on 1,3,7 and 14 day after mechanical ventilatory .The correlation between the oxygenation index and P A-a DO2 was compared in the two groups .Results①We found that the two group′s age, gender, serum creatinine (Cr), blood ALT, AST, total bilirubin (TBil), oxygenation index and PA-a DO2 values before the mechanical ventilation has no statistical difference, and there also has no statistical difference in oxygenation index and P A-a DO2 values on the first day after mechanical ventilation ( P>0 .05 ) .②There were statistical differences between the two group′s oxygenation index and P A-a DO2 values on the 3, 7, 14 day after mechanical ventilation ( P<0.05), the successful weaning ventilation group′s oxygenation index was higher than that of the failure weaning ventilation group.The numbers were (163.65 ±25.33) mm Hg vs.(112.29 ±29.95) mm Hg, (172.68 ±22.09) mm Hg vs.(121.589 ±23.35) mm Hg, (231.9 ±37.56) mm Hg vs. (115.00 ±21.69) mm Hg, and it′s PA-aCO2 values were lower, the numbers were (186.65 ±55.05) mm Hg vs.(310.50 ±51.16) mm Hg, (120.41 ±33.91) mm Hg vs.(347.69 ±50.56) mm Hg, (86.38 ±29.91) mm Hg vs.(347.55 ±49.16) mm Hg.③ The PA-a DO2 was significantly negatively correlated with the oxygenation index (r=-0.698, P=0.000).Conclusion The dynamic monitoring of PA-a DO2 values is helpful for evaluation of the treatment effects and for predicting whether patients can wean ventilation or not , who was diagnosed ARDS caused by lung infection and require mechanical ventilation.
Keywords：Aveolar-artery partial pressureLung infectionARDSWean ventilation
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 76-79 )