Risk of reducing endotracheal reintubation in patients with respiratory failure after abdominal surgery by noninvasive ventilation
Dong Hong
Qian Qin-juan
Zhang Ying
Fei Zhi-yong
Kang Zhen
Abstract：Objective To evaluate the effect of noninvasive ventilation (NIV) on endotracheal reintubation in patients with hypoxic respiratory failure after abdominal surgery.Methods The patients with hypoxic respiratory failure within 7 days after abdominal surgery in our hospital ICU were randomly divided into two groups according to the random number table method.The patients were treated with NIV (NIV group,n =173) treatment or standard oxygen treatment (standard oxygen therapy group,n =175).The treatment was performed for 30 days from completion of randomization,or to leave ICU.The endotracheal reintubation rate,noninvasive ventilation time,treatment-related infection and mortality were compared between the two groups.Results The number of patients endotracheal re-intubated in the NIV group was significantly lower than that in the standard oxygen therapy group [57 (32.9％) vs.80 (45.7％),x2 =5.940,P =0.015].Compared with the standard oxygen therapy group,the NIV group had no significant improvement in noninvasive ventilation time [(25.5 ± 4.2) d vs.(20.6 ± 3.8) d,t =11.415,P ＜ 0.001].The patients in the N IV group had fewer infections [54 (31.2％) vs.86 (49.1％),x2 =11.630,P ＜ 0.001].The patients in group NIV had fewer patients with pneumonia within 7 days [17 (9.8％) vs.39 (22.3 ％),x2 =10.002,P =0.002] and 30 days [25 (14.5％) vs.52 (29.7％),x2 =11.763,P ＜ 0.001].There was no statistically significant difference in ICU hospitalization time between the two groups (P ＞ 0.05).Multivariate analysis showed that NIV was negatively correlated with endotracheal reintubation (OR =0.496,95％ CI 0.231 ～0.817,P =0.007).Conclusion Noninvasive ventilation can reduce the risk of endotracheal reintubation in patients with hypoxic respiratory failure after abdominal surgery compared with standard oxygen therapy.
Keywords：Noninvasive ventilation(NIV)Endotracheal reintubationRespiratory failure
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1011-1015 )