Mechanism of platelet dysfunction in patients with sepsis
Fu He-peng
Zhang Yu-xiang
Abstract：Sepsis is a systemic inflammatory reaction induced by infection, which can cause shock, multiple organ failure and even death. Severe sepsis often causes coagulation disorders, especial-ly platelet quality and quantity changes. The role of platelets in sepsis pathogenesis remains unclear. The changes of platelet quality and quantity were significantly correlated with the severity and mortality of sep-sis patients. The mechanism of platelet dysfunction also has the hotspot of nowadays research.
Keywords：SepsisPlatelet dysfunctionInfectionInflammatory reactionImmune re-action
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 873-877 )