Progress of relationship between IL-33/ST2 signaling and sepsis
Kong Xia
Zhang Xin-chao
Abstract：Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection.Soluble suppression of tumorigenicity 2 (sST2) concentrations could be increased in inflammatory diseases.This paper reviews the latest progress on the relationship between ST2/IL-33 signaling and sepsis, and has drawn the Conclusion that both the ST2 and IL-33 concentrations are increased in sepsis patients.Serum IL-33 concentration will change with the progress of sepsis;its trend of change is valuable in predicting the outcome of sepsis.These may have some research value and prospects in diagnosing sepsis.
Keywords：SepsisInterleukin-33(IL-33)ST2DiagnosisPrognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 790-793 )