Assessment of the value of APACHE Ⅱ score system, SOFA score and procalcitonin in Acinetobacter baumannii bloodstream infection
Zhou Wen-jie
Zhang Xiao-ya
Zhang Jun
Wang Xiao-hong
Yang Xiao-jun
Ma Xi-gang
Abstract：Objective To explore acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ),sequential organ failure assessment (SOFA) score and procalcitonin in Acinetobacter baumannii bloodstream infection.Methods Clinical data was collected on 112 patients with Acinetobacter baumannii bloodstream infections during January 2009 to December 2015,including gender,age,APACHE Ⅱ score at admission and APACHE Ⅱ score on bloodstream infections day,SOFA score at admission and SOFA score on blood stream infections day,procalcitonin,length of ICU stay,the total hospitalization days,body temperature,white blood cell count,neutrophilic granulocyte percentage,28 d end etc.The receiver operating characteristic curve (ROC) was drawn and the area under the curve (AUC) was calculated.APACHE Ⅱ,SOFA score and procalciton in Acinetobacter baumannii bloodstream infections in patients were compared to assess the value of prognosis.Results In 112 patients,66 cases died (58.93％),46 cases survived (41.07％).Compared with group survival,death group admission APACHE Ⅱ score (20.47± 7.39 vs.12.59 ± 5.26,P ＜ 0.001),bloodstream infections on APACHE Ⅱ score (26.56 ±8.16 vs.13.09±4.99,P ＜ 0.001),admission SOFA score (8.94±4.17 vs.5.11 ±2.44,P ＜ 0.001),bloodstream infections on SOFA score (11.86±4.72 vs.4.24± 3.06,P ＜ 0.001) were significantly increased.Death and survival group,two groups of procalcitonin comparative difference was statistically significant (P ＜ 0.001).Individual indicators in the bloodstream infections on APACHE Ⅱ score prediction value was the largest,AUC value of 0.920 (95％ CI 0.871～0.969),when the cutoff value of 16,the sensitivity of 92.4％,78.3％ specific degrees.PCT joint bloodstream infections on APACHE Ⅱ score and SOFA score the AUC value was 0.935 (95％ CI 0.893～0.977),in the joint index prediction value was bigger.Conclu sion APACHE Ⅱ score,SOFA score and procalcitonin can be used as Acinetobacter baumannii bloodstream infection prognostic index.PCT joint bloodstream infections on APACHE Ⅱ score and SOFA score is important for assessing the severity and prognosis.
Keywords：Acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ)Sequential organ failure assessment (SOFA)Procalcitonin (PCT)Acinetobacter baumanniiBloodstream infection
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 221-225 )