The catastrophic antiphospholipid syndrome/Asherson's syndrome：an overview and update
SHEN Si-yu
ZHU Pei-yuan
FU Xiao-dong
Abstract：Catastrophic antiphospholipid syndrome (CAPS), i.e.Asherson's syndrome, is characterized by diffuse small vessel thrombosis and acute multiple organ involvement which resulting in multiorgan failure over a short period of time. Although less than 1% of patients with the antiphospholipid syndrome ( APS ) develop this complication, unfortunately, the mortality is extreme high.The purpose of this paper is to summarize characteristics of CAPS which including clinical manifestation, pathogenesis, classification criteria, therapy strategy and prognosis.In parallel with CAPS registry, CAPS task force should pay more attention in advanced treatment recommendations revised which maintaining clinical long-term remission and increasing survival rate in the future.
Keywords：Catastrophic antiphospholipid syndrome( CAPS)Asherson's syndromePathogenesisClinical characteristics
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1143-1146 )