Effects of electro -acupuncture of Zusanli points on kidney ischemia injury and free radical injury after hemorrhagic shock in rat
Abstract：Objective To investigate the effects of electro -acupuncture of Zusanli points on ischemia injury in kidney after hemorrhagic shock in rats .Methods Forty SD rats were randomly divided into four groups ( n=10 ): electro -cupuncture Zusanli points group ( EA ) , sham electro -acupuncture group (SEA), fluid resuscitation (FR) and model control group (MC).Fluid replacement was performed in Group of FR 10 minutes after blood loss .Bilateral Zusanli points ( ST36 ) were electro-acupunctured with constant voltage (4 Hz, 4 V) for 25 min approximately 10 min after blood loss, while no -acupoint control , points was conducted in SEA group , there was nothing to do after blood loss in MC group .The kidney blood flow ( KBF) and creatinine ( Cr) were measured 3 h and 6 h after hemorrhage .The rate of tissue water content ( WG ) and malondialdehyde ( MDA ) 6 h after hemorrhage were also determined .Results 3 h and 6 h after blood loss , blood Cr levels of EA group were significant lower than those of SEA and MC group;the KBF of EA was significant higher than those of SEA and MC (all P<0.05);MDA and WG of EA group in kidney were significant lower than those of SEA and MC group (all P<0.05) 6 h after blood loss.Conclusion The results suggested that electro-acupuncture of Zusanli points alleviate kidney ischemia injury in rats after hemorrhagic shock .
Keywords：Hemorrhage shockZusanliElectro-acupunctureKidneyIschemia
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1036-1038 )