Neutrophil-to-lymphocyte ratio predicts contrast-induced nephropathy in patientsundergoing coronary computed tomographic angiography
Abstract：Objective We investigated the relationship between baseline neutrophil -to -lymphocyte ratio ( NLR ) and contrast -induced nephropathy ( CIN ) with computed tomographic angiography ( CCTA ) . Methods The study selected patients undergoing CCTA in Department of Cardiology in our hospital , giving venous blood pre -examination , 24 hour and 48 hour respectively , to see the changs related indicators , compare , NLR in CIN patients with non-CIN patients .Results In this study, a total of 382 patients were enrolled .A total of 24 patients developed CIN .Both NLR ( P<0.001) and C-reactive protein (P<0.001) levels were significantly higher in the CIN group when compared with the non-CIN group.There was a stronger correlation in patients with a known history of CKD (r=0.281, P=0.012) than in patients with no history of chronic kidney disease (CKD), and in patients with a history of diabetes mellitus (DM) than in patients with no history of DM (r=0.359, P<0.001).Multivariate logistic regression analysis revealed that advanced age , DM, baseline glomerular fitration rate( GFR) , NLR, and left ventricular ejection fractions ( LVEF) were independent predictors of CIN.Conclusion The NLR may be used as a simple and reliable indicator of CIN in patients who underwent CCTA .
Keywords：Contrast-induced nephropathy ( CIN)Neutrophil-to-lymphocyte ratio ( NLR)Coronary computed tomographic angiography ( CCTA)
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1017-1021 )