The validation of GRACE risk model in AMI patients around Soochow area
Abstract:Objective To validate the GRACE risk score system of STEMI and NSTEMI in Soochow area .Methods A total of 312 patients with STEMI and NSTEMI were identified and the GRACE risk score were calculated for each patient .The validity of the model was assessed with discrimination , calibration and decision curve analysis .Results GRACE risk score demonstrated good discrimination (C-index 0.720, 95%CI 0.607~0.833).The calibration plot demonstrated that the risk was underestimated for low risk cohorts .Decision curve analysis showed that GRACE risk score system was suitable for all the patients enrolled in the validation cohorts .Conclusion GRACE risk score could make a good risk stratification of ACS subgroup ( STEMI and NSTEMI ) in Soochow area . Furthermore it was beneficial for stratifying , making individualized treatment and improving the prognosis.At present, the calibration ability of GRACE risk score system should be improved , validating with larger sample size of the risk stratification system is necessary .
Keywords:Acute myocardial infarction ( AMI)Global registry of acute coronary events ( GRACE)Model validation
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:6( 1003-1008 )
