The value of early stage BIS m onitoring in the assessment of sepsis
ZHANG Li
Abstract：Objective To investigate the continuous bispectral index ( BIS) monitoring for the early diagnosis , disease severity evaluation in patients with sepsis encephalopathy .Methods This retrospective analysis contained 80 patients with sepsis admitted in our department , and these patients were divided into encephalopathy group (experimental group ) and non-encephalopathy group ( control group).After ICU admission, all the patients received standard sepsis recovery treatment ( sepsis treatment guide2012).Immediately after ICU admission, they were continuously monitored the BIS for 24 h in order to get a 24-h-average; at the same time , the Glasgow coma scale ( GCS ) and acute physiology and chronic health evaluation Ⅱ( APACHEⅡ) were recorded , and blood samples were taken for the detection of serum PCT and S -100 B protein content .The average BIS values , PCT, S-100 B protein, GCS score and APACHEⅡ score were compared between the groups , and correlation analysis was also done between the groups .Results ①When compared the encephalopathy group and non -encephalopathy group , the BIS, PCT, S -100B protein, GCS score and APACHEⅡ score had significant difference(P<0.01).②The BIS value was positively correlated with GCS , APACHEⅡscore significantly (P<0.01).Conclusion Continuous BIS monitoring can evaluate sepsis severity in patients with brain injury , and to make an early diagnosis.
Keywords：SepsisSepsis encephalopathy(SAE)Bispectral index (BIS)Early diagnosisPrognosisGlasgow coma scale ( GCS)
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 982-985 )