Clinical study of 111 patients with diffuse interstitial lung disease
Abstract：Objective This study aimed to analyze the disease spectrum distribution of diffuse interstitial lung disease and increase diagnostic and therapeutic level of this kind of disease.Methods Clinical materials of one hundred and eleven patients with diffuse interstitial lung disease hospitalized into Peking Union Medical College Hospital from 2006 to 2013 were collected.Causes, symptoms, lung function, blood gas and pathological characters were analyzed retrospectively.Results Cough, dyspnea were the major symptoms and nearly half of the patients had hypoxemia.The incidence of acropachia of patients with interstitial lung disease was higher than that of the patients with interstitial lung disease associated with connective tissue disease, but the latter had more specific contact -type ( both P <0.05).83.9% patients had restrictive ventilatory functional disturbance.The major radiological characters by high-resolution computed tomography included patch, swollen lymph nodes, frosted glass like change, pleural disease, nodular and grid shadow.The incidence of nodular shadow of the patients with interstitial lung disease associated with connective tissue disease was higher than that of the patients with interstitial lung disease ( P <0.05 ) .The major pathological type of interstitial lung disease included nonspecific interstitial pneumonia (19.8%), extrinsic allergic alveolitis (18.9%), interstitial lung disease associated with connective tissue disease (11.7%), sarcoidosis (8.1%).Conclusion Confirming clinical character of diffuse lung disease could reduce missed diagnosis, misdiagnosis and mistherapy and raise diagnosis and therapeutic levels.
Keywords：Lung diseaseInterstitialClinical study
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 722-725 )