The application of Ranson scoring system on the treatment of severe acute pancreatitis with continuous blood purification
Abstract：Objective To explore the Ranson scoring system guides the treatment timing in severe acute pancreatitis (SAP) with continuous blood purification (CBP).Methods A total of 86 SAP patients were divided into three scores sections randomly according to Ranson scoring system:3~4 points, 5~6, and>6 points, and each section was divided into CBP group and control group.The length of stay ICU, the mortality of 28 d and the levels of inflammatory cytokines ( TNF-α, IL-10) were compared between the two groups in each section. Results The ICU length of stay was significantly reduced in CBP group in each section.The 28-day mortality was similar between the two groups in 3~4 points section and>6 points section, but significantly lower in CBP group than in control group at the 5~6 points section.The levels of inflammatory cytokines in serum were decreased after CBP treatment in each section.The inflammatory cytokines were different between CBP group and control group in 3 ~4 points and 5 ~6 scores segment, but no significant difference in >6 points scores segment.Conclusion The best time of treatment SAP patients with CBP is 5 ~6 scores in Ranson scoring system.
Keywords：Ranson scoring systemSevere acute pancreatitis(SAP)Continuous blood purification(CBP)
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 351-354 )