A case report and related literature review about thecharacteristics of acute myocardial infarction combined with idiopathic thrombocytopenia purpura
Abstract：Objective To investigate the clinical features, pathogenesis, prevention and treatment of acute myocardial infarction ( AMI ) combined with immune thrombocytopenic purpura ( ITP) .Methods We reported a case of an old man who suffered acute myocardial infarction twice during the treatment of ITP and reviewed data available in the literature and discussed the clinical characteristics, pathogenesis, prevention and treatment.Results Only 11 cases reports of AMI with ITP are available in the literature ( including this case) .All of ITPs were chronic with an average age of 62.64, Male/Female ratio was 6∶5.Among them, 9 patients had one or more risk factors for coronary heart disease.Conclusion TP patients with AMI may exist special mechanism: beside endothelial injury and microcirculation, we should considered the process of ITP treatment.However, careful attention must be paid for a rapid rise in the plateletcount, which may induce myocardial infarction or stroke, particularly in the elderly patients and in patients withcoronary risk factors.For patients with large area STEMI and no signs of bleeding caused by ITP, emergency coronary angiography and postoperative antiplatelet therapy are all safe.
Keywords：Immune thrombocytopenic purpura ( ITP)Acute myocardial infarction ( AMI)Clinical characteristics
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 323-326 )