Bacterial contamination of ventilator circuit and its influence on ventilator associated pneumonia in mechanically ventilated patients
LI Hong-jie
GAO Hong-mei
Abstract：Objective To survey the status of ventilator circuit with bacterial contamination and the influence on morbidity of VAP associated with ventilator circuit changes in mechanically ventilated patients.Methods According to the frequency of ventilator circuit changes, 161 patients with mechanical ventilation in ICU were divided into different groups.Bacterial culture of different locations in ventilator circuit and sputum culture were made every day in 81 patients in order to compare the rate of bacterial growth, the difference of morbidity of VAP and prognosis.Results Gram-negative bacteria is superior in ventilator circuit.Statistically, the rate of bacterial growth ( 84.65%) was the highest in circuit and artificial airway joints(P<0.01).The consistent rate of bacterial culture of inspiratory tube and sputum culture(41.49%)was low(P<0.01).The rates of bacterial growth in inspiratory tube, exspiratory tube and artificial airway joints are positively correlated with time ( r =0.9694, 0.9082, 0.6384) .The time sequence of bacteria growth were at the artificial airway joints, inspiratory tube and exspiratory tube.There were no statistical differences in the morbidity of VAP and prognosis among in the groups which were divided by frequency of ventilator circuit changes( P>0.05) .Conclusion The rate of ventilator circuit with bacterial contamination in mechanically ventilated patients is high, but it has no effect on the morbidity of VAP by adjusting the frequency of ventilator circuit changes.
Keywords：ICUVentilator-associated pneumonia( VAP)BacteriaManagement of ventilator circuit
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 267-270 )