The risk factors for developing hypernatremia and other factors aff ecting the prognosis in sepsis patients
Abstract：Objective We aim to explore the risk factors for developing hypernatremia in patients with sepsis and the prognosis of sepsis patients with or without hypernatremia was also assessed. Methods To analyze the data from patients with sepsis, both univariate and multivariate logistic regression analyses were applied, using 10 indices, including age, gender, Acute Physiology and Chronic Health EvaluationⅡ scores ( APACHEⅡ) , C -reactive protein ( CRP ) levels and so on. Clinical prognosis such as mortality, hospital duration of patients with or without hypernatremia was also compared.Results APACHEⅡ score [ odds ratio( OR ) 1.15; 95% confidence interval ( CI ) 1.022~1.294] was found to be the only independent risk factor for hypernatremia in patients with sepsis.Moreover, these patients with hypernatremia showed significantly longer length of hospital stay and mechanical ventilation ( MV) time and higher rates of complications and mortality .Conclusion APACHEⅡscore is an independent risk factor for hypernatremia in patients with sepsis .Moreover,the clinical outcome of patients with hypernatremia is significantly poorer than the non -hypernatremia group.
Keywords：HypernatremiaSepsisRisk factorsPrognosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 203-206 )