Serum uric acid as an independent predictor for hospital mortality and cardiac shock in patients with acute myocardial infarction
CHEN Du
LU Shi-qi
XU Feng
Abstract：Objective To investigate the predictive value of serum uric acid for hospital mortality and cardiac shock in patients with acute myocardial infarction.Methods A total of 181 patients with myocardial infarction ( male:n=154, 85.1% vs.female: n=27, 14.9%) admitted to the First Affiliated Hospital of Soochow University from Sep.2010 to Sep.2012 were enrolled.They were divided into an observation group (n=79, 43.6%) of hospital mortality and cardiac shock and a control group (n=102, 56.4%).The levels of serum uric acid were measured from the vein blood in the morning of the 2nd day after admission.Clinical data were analyzed by univariate and multivariate logistic regression model.Results The serum level of uric acid (μmol/L) of observation group was significantly higher than the control group [350.5 (300.0, 457.0) vs.326.5 (279.5, 390.0), P=0.031].Serum uric acid (OR=1.006, 95%CI:1.002 to 1.010, P=0.002) and diabetes mellitus (OR=2.459, 95% CI:1.064 to 5.680,P=0.035) were both determined as the independent risk factors of hospital mortality and cardiac shock by multivariate logistic regression model.Conclusion Serum uric acid is an independent risk factor for hospital mortality and cardiac shock in patients with acute myocardial infarction.Patients with high level of serum uric acid at admission should be paid more attention, and effective measures should be taken for them.
Keywords：Myocardial infarctionUric acidCardiac shockHospital mortalityRisk factor
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1006-1008 )