The impact of statins for the network between blood coagulation and inflammation in sepsis
LI Yong-lin
ZHOU Hong
Abstract：Sepsis is a systemic inflammatory response syndrome by infection , which can develop into severe sepsis or sepsis shock.The case fatality rate is still 30%~70%, although with the evolutive anti-inflective therapy and multi-organ support therapy.It was found that lipid metabolism was chaotic in sepsis in some recent studies. Stains are known for reducing blood lipid and improving the atherosclerosis, but they are also noted by improving inflammation, coagulation,endothelial function and so on in sepsis.This paper will introduce the impact of statins for the network between blood coagulation and inflammation in sepsis.
Keywords：Lipid metabolismSystemic inflammatory response syndrome ( SIRS)BloodCoagulation functionStatins
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 985-987 )