Clinical analysis of the target volume control ventilation in the treatment of neonatal respiratory distress syndrome
GUAN Xiao-yan
Abstract：Objective To compare the efficacy and complications between synchronized intermittent positive pressure ventilation combined volume controlled ventilation ( SIPPV+VG) with the traditional assist/control ( A/C ) ventilation in the treatment of neonatal respiratory distress syndrome ( NRDS) and guide the clinical application .Methods Sixty -six cases of NRDS were randomly divided into SIPPV+VG group and A/C group, 33 cases in each group.SIPPV+VG group received synchronized intermittent positive pressure ventilation combined volume controlled ventilation , A/C group received assist /control ventilation .Oxygenation status and complications were compared between two groups.Results P/F and a/APO2 were significantly increased with time in both group (F=31.25, 16.82, P<0.05), while P/F and a/APO2 in SIPPV+VG group were significantly higher than those in A/C group(F=9.54、 6.73, P <0.05).Duration of oxygen therapy and mechanical ventilation in SIPPV+VG group was significantly less than that in A/C group.The incidence of ventilator associated pneumonia ( VAP) and gas leakage in SIPPV +VG group were significantly less than those in A/C group.Conclusion SIPPV +VG ventilation has advantages in safety and efficacy , and is worthy of clinical application .
Keywords：Neonatal respiratory distress syndromeSynchronized intermittent positive pressure ventilationVolume controlled ventilationAssist/control ventilationEfficacy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 833-836 )