Effect of ambroxol hydrochloride atomization on the myeloid cells start receptor-1(sTREM-1) of patients with ventilator associated pneumonia
LIANG Qun
WANG Cong
Abstract：Objective To observe the changes of myeloid cells start receptor -1 (sTREM-1) in the ventilator associated pneumonia patients with ambroxol hydrochloride atomization combined western medicine .Methods 64 patients with ventilator associated pneumonia admitted to intensive medicine ward of Heilongjiang University of Traditional Chinese Medicine from March 2010 to March 2014 , were randomly divided into treatment group ( 32 cases ) and control group ( 34 cases ) .The patients of two groups were given standard treatment , treatment group on the basis of western medicine treatment accepted ambroxol hydrochloride atomization , 4 times a day, every time 20 mL, and treatment time of two groups was 7 days.Results After the treatment, clinical pulmonary infection score improved in two groups (P<0.05), clinical symptom was better in the treatment group than in control group , the difference was statistically significant (P<0.05);sTREM -1 levels in two groups after treatment were decreased ( P <0.05 ), the treatment group decreased more significantly than control group , the difference was statistically significant ( P <0 .05 ) .Conclusion On the basis of western medicine treatment, ambroxol hydrochloride (mu comfortable) atomization can reduce clinical pulmonary infection score, improve the treatment efficiency , which is related with the decrease of sTREM -1 level in the patients with ventilator associated pneumonia .
Keywords：Ventilator associated pneumonia(VAP)Myeloid cells start receptor-1(sTREM-1)Ambroxol hydrochloride atomizationThe clinical pulmonaryinfection score
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 803-805 )