Risk stratification assessment of pulmonary embolism with the GRACE risk score
Abstract：Objective To explore the applicability and extend the use of the Global Registry of Acute Coronary Events ( GRACE) risk score to acute pulmonary embolism ( PE) .Methods A case-control study of 103 consecutive patients admitted with acute PE was performed .The GRACE risk score , Geneva score , simplified Pulmonary Embolism Severity Index , and European Society of Cardiology risk scores were tested for the prediction of the primary end point: all -cause 30 -day mortality. Comparisons between GRACE and the other risk scores were performed using receiver operating characteristic area under the curve .Results All-cause 30-day mortality was observed in 18 .4% of the patients.Unlike the other classifications , no adverse outcomes were observed in patients classified as low risk using the GRACE risk score (100%negative predictive value for GRACE risk score ≤109). The GRACE score showed greater discriminative performance than the Geneva score ( area under the curve 0.623, 95%CI 0.53 to 0.71), European Society of Cardiology (area under the curve 0.662, 95%CI 0.57 to 0.76), and simplified Pulmonary Embolism Severity Index ( area under the curve 0.705, 95%CI 0.61 to 0.80).Conclusion Our results have demonstrated that the GRACE risk score can accurately predict 30-day mortality in patients admitted for acute PE .
Keywords：Acute pulmonary embolismGlobal Registry of Acute Coronary Events ( GRACE) scoreGeneva scoreSimplified pulmonary embolism severity index (sPESI)European Society of Cardiology (ESC) risk scoresMortality
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 338-341 )