Clinical usefulness of platelet counts and sustained systemic inflammatory response sysdrome predict acute pancreatis combined with multipe organ dysfunction syndrome
Abstract：Objective To determine the usefulness of platelet counts andsustained systemic inflammatory response sysdrome (SIRS) in predicting acute pancreatis (AP) combined with multipe organ dysfunction syndrome (MODS).Methods A retrospective analysis was made in 152 patients with acute pancreatis. These patients were divided into 3 groups according to the sustained SIRS:group A (non-SIRS), group B (sustained SIRS≤3 days) and group C (sustained SIRS＞3 days). The platelet count, the incidence of MODS and the mortality rate were compared in every group. A receiver operating characteristic (ROC) curve of platelet counts for predicting AP combined with MODS was also constructed. Results Platelet counts showed significant differences among the three groups. The incidence of MODS and mortality rate was significantly higher in patients with SIRS for＞3 days compared with those in the other groups. Likelihood ratios of platelet counts and SIRS for＞3 days for predicting MODS were 5.29 and 12.65 respectively. Platelet counts(80×109/L) had a sensitivity of 88.89% and a sepcificity of 83.2% for predicting MODS. Conclusion Platelet counts and sustained SIRS are useful for predicting AP combined with MODS. Platelet counts can be used as a simple laboratory test for predicting MODS.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 86-87 )