Effect of preload on hemodynamic and oxygen metabolism in septic shock patients
Abstract：Objective To observe the effect of preload on hemodynamic andoxygen metabolism in patients with septic shock.Methods 10 patients with septic shock induced by gram negative bacteria were admitted to this study group,parameters of hemodynamic and oxygen metabolism in defferent preload were measured.Results By fluid resuscitation,as the pulmonary artery wedge pressure increased from 0.8±0.3 to 1.6±0.4 kPa,cardiac index rose from 2.0±0.4 to 3.9±0.9 L.min-1.m-2,but systemic vascular resistance index decreased from 3 291.9±810.6 to 1 362.2±382.9 dyn.s.cm-5.m2 significantly (P＜0.05).Meanwhile,oxygen delivery index rose from 284.3±77.0 to 558.5±131.1 ml.min-1.m-2,and oxygen consumption index also increased from 99.7±52.3 to 140.7±45.0 ml.min-1.m-2 remarkably(P＜0.05).Conclusion Hemodynamic classification was decided by cardiac preload,fluid resuscitation is very important in septic shock therapy.
Machine-generated Keywords：
Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 79-81 )