Studies on Interleukin-1 activities of peripheral blood mononuclear adhered cells in patients with coronary heart disease
ZHOU Rong-bin
CUI Zhi-x ian
JIN Bo-quan
Abstract：Objective To study the roles of cell immune reaction,especially the concentration changes of interleukin-1 to pathogenesis of elderly coronary heart disease(CHD).Methods Quantitative measuring the concentration of interleukin-1 which produced by peripheral blood mononucl ear adhered cells of elderly CHD patients by bioactive measuring method.Results The activity of IL-1 was significantly increased in patie nts with CHD than that in normal controls.Conclusions The activity of IL-1in patients with CHD was significantly increased,this may play an important part in pathogenesis of atherosclerosis by the role of vascular smooth cell,epithelia cell,complements and inflammation reactions.
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Publication Date：2001-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 10-11 )