Evaluation of the efficacy of remimazolam sedation combined with ultrasound-guided fascia iliaca compartment block in elderly patients undergoing hip arthroplasty
WANG Huai-qing
NI Wei-feng
HUANG Xiao-yan
DU Li
LI Shou-chun
Abstract：Objective To evaluate the efficacy of combined remimazolam sedation with ultrasound-guided fascia iliaca compartment block(FICB)in elderly patients undergoing hip arthroplasty(HA).Methods Eighty elderly patients who received HA treatment at our hospital from March 2023 to August 2024 were selected and divided into a control group and an observation group according to randomized numerical table method,with 40 cases each.The control group routinely underwent combined spinal-epidural anesthesia in the lateral decubitus position.The observation group received intravenous remimazolam at 0.15 mg/kg,followed by ultrasound-guided FICB on the affected side.Following successful block,the patient was positioned in the lateral decubitus position for combined spinal-epidural anesthesia.The heart rate and mean arterial pressure of the two groups were compared before anesthesia,during neuraxial puncture,during skin incision,and after surgery.The pain visual analogue score(VAS)was used to compare the pain levels of the two groups before anesthesia,during neuraxial puncture and positioning,and at 2 h,4 h,8 h,24 h,and 48 h after surgery.The incidences of postoperative salvage analgesia and adverse reactions(irritability,dizziness,nausea and dry mouth)were compared between the two groups.Results During the positioning for spinal canal puncture,the control group exhibited significantly higher heart rates[(91.53±5.12)beats/min vs.(82.25±3.57)beats/min]and mean arterial pressures[(102.31±8.55)mm Hg vs.90.53±8.21)mm Hg]compared to the observation group(P<0.05).Patients in the control group exhibited significantly higher VAS scores during the positioning phase for spinal canal puncture(8.62±0.49 vs.5.18±0.55)and at 8 hours post-operatively(3.76±0.49 vs.2.94±0.46),24 hours post-operatively(3.36±0.52 vs.2.64±0.47),and 48 hours post-operatively(2.07±0.50 vs.1.32±0.57)than the observation group(P<0.05).The incidences of postoperative rescue analgesia(20.0%vs.2.5%)and agitation(15.0%vs.0.0%)were higher in the control group than in the observation group(P<0.05).Conclusions Remimazolam sedation combined with ultrasound-guided FICB administration in elderly patients undergoing HA significantly enhances perioperative analgesia,promotes circulatory stability,and reduces postoperative complications.
Keywords：UltrasonographydopplerAgedArthroplastyreplacementhipAnesthesia and analgesia
Publication Date：2026-01-19
Online Publishing Date：2026-03-09(First online date of this platform, not the publication date of the document)
Pages：5( 43-47 )