Research progress on the application of adipose-derived stromal vascular fraction in orthopedics
HOU Wai-fang
ZHAO Qing-he
CHEN Yong-feng
DU Tian-shu
WU Hai-ning
YE Zi
ZHANG Ran-ran
ZHAO Chen-xi
CHEN Wen-jing
ZHANG Da-wei
Abstract：Stromal vascular fraction (SVF) is a heterogeneous cell population extracted from autologous adipose tissue containing a variety of stem cells including mesenchymal stem cells and rich extracellular matrix. It has the functions of tissue repair, blood vessel regeneration promotion and immune regulation due to its rich cell components. SVF has been reported to show good therapeutic effect in the treatment of various orthopedic diseases. This paper will summarize the extraction, preparation, action mechanism and application of SVF in the field of orthopedics, in order to provide basis for the treatment prospect of SVF in orthopedic related diseases.
Keywords：Stromal vascular fractionMesenchymal stem cellsExtracellular matrixImmunomodulationReview
Publication Date：2025-09-19
Online Publishing Date：2025-09-29(First online date of this platform, not the publication date of the document)
Pages：8( 835-842 )