Meta-analysis of the clinical efficacy and prognosis of UBE-TLIF and MIS-TLIF in the treatment of degenerative lumbar diseases
WANG Xin
ZHOU Yan-jie
XU Hai-tao
LIU Jun
LI Bo
Abstract：Objective To compare the clinical efficacy and prognosis of unilateral biportal endoscopic lumbar interbody fusion(UBE-TLIF)and minimally invasive transforaminal lumbar interbody fusion(MIS-TLIF)in the treatment of degenerative lumbar diseases.Methods Conduct a comparative clinical study on the treatment of degenerative lumbar diseases with UBE-TLIF and MIS-TLIF from the establishment of our database to May 2024,by searching English and Chinese databases including PubMed,Embase,Web of Science,CNKI,and Wanfang Database.Extract observation indicators from each study comprehensively,including VAS,ODI,average operation time,intraoperative blood loss,postoperative drainage volume,preoperative and postoperative HB,fusion rate,complications,etc.,and analyze the quality of the included literature.Meta-analysis was conducted using RevMan 5.4 software.Results A total of 15 studies with 1077 participants were included,containing 503 cases undergoing UBE-TLIF and 574 cases undergoing MIS-TLIF.The results of meta-analysis showed that there were statistically significant differences between the UBE-TLIF group and the MIS-TLIF group in postoperative back VAS score,postoperative ODI score,average operation time,intraoperative blood loss,estimated blood loss,postoperative drainage,total blood loss,and postoperative infection rate(all P<0.05).There were no statistically significant differences between the two groups in postoperative leg VAS score,preoperative and postoperative HB,fusion rate,and other postoperative complications(all P≥0.05).Conclusions Compared with the MIS-TLIF group,the UBE-TLIF group had lower intraoperative blood loss,lower estimated blood loss,lower postoperative drainage,lower total blood loss,lower postoperative infection rate,faster postoperative recovery,shorter hospital stay,but longer operation time.Compared with the mainstream surgery MIS-TLIF,UBE-TLIF has the advantages of less trauma and lower invasiveness,making it another reliable surgical option for the treatment of degenerative lumbar diseases.
Keywords：Minimally invasive surgical proceduresSpinal fusionLumbar vertebraeEndoscopesMeta-analysis
Publication Date：2025-04-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：16( 366-381 )