Application effect of decalcified bone matrix in traumatic bone defects of limbs
WANG Xiao-bo
LI Wen-feng
WANG Ao-ao
ZHANG Chen-xi
LI Li
HOU Shu-xun
ZHAO Yan-tao
Abstract：Objective To retrospectively study the effect of a new decalcified bone matrix in the treatment of traumatic bone defects in extremities.Methods Thirty patients treated with decalcified bone matrix in the Fourth Medical Center of the PLA General Hospital from January 2021 to December 2021 were followed up and evaluated.The time points included 3,6,and 12 months.The bone healing and complications were evaluated.Results Thirty patients were followed up in different forms,all of them achieved bone healing and recovered well.The healing time was 10-16 weeks,with an average of(12.70±1.92)weeks.The patients'Lane Sandhu X-ray scores at 1,3 months after surgery and at the last follow-up were higher than those before surgery,and the scores at 3 months and the last follow-up were higher than those at 1 month after surgery with a statistically significant difference[Lane Sandhu X-ray scores:(0±0)preoperatively,(2.17±0.80)1 month postoperativel,(2.17±0.80)3 months postoperatively,(7.30±1.29)at the last follow-up](P<0.05).No adverse reaction related to decalcified bone matrix implants occurred in the follow-up period of 30 patients.No infection,internal fixation,implant loosening or other complications occurred after surgery.Conclusions The new decalcified bone matrix has a good effect in the treatment of traumatic bone defects in extremities.
Keywords：FracturesboneBone transplantationAllograft boneBone defect
Publication Date：2023-12-19
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 911-916 )