A correlation study between diabetes mellitus and prosthetic joint infection after the artificial joint replacement
ZHAO Zhen
MA Bao-an
LONG Hua
NIU Shun
Abstract：Objective To investigate the effects of diabetes on prosthetic joint infection (PJI) after the artificial joint replacement. Methods Clinical data of 1799 patients who underwent primary total hip and knee arthroplasty from January 2010 to March 2016 in our hospital were selected for this retrospective cohort study. All patients were divided into the diabetes group (n =361) and control group (n =1438). Conditional Logistic regressions were run to calculate the odds ratios (ORs) and the 95％ confidence intervals (CIs). Results The risk of PJI for diabetic patients was 1.83 times (95％ CI: 1.01 - 3.32, P ＜ 0.05) higher than that for the non-diabetic patients. The risk was higher among the diabetic patients with bilateral artificial joint replacement (OR: 7.2; 95％ CI: 1.2 - 43.6; P ＜ 0.05) than the patients with unilateral artificial joint replacement (OR =1.9). Diabetic patients and patients with abnormal glucose tolerance took higher risks of PJI than patients with normal blood glucose by 7.5 times (95％ CI:1.4 - 38.7, P ＜ 0.05) and 5.8 times (95％ CI: 1.1 - 31.6, P ＜ 0.05), respectively. Conclusions Diabetes and abnormal glucose tolerance will statistically increase risks of PJI after the artificial joint replacement. PJI is more likely to occur in diabetic patients with bilateral artificial joint replacement.
Keywords：Joint prosthesisDiabetes mellitusInfectionArthroplastyreplacementhipknee
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 301-306 )