The treatment of giant cell tumors of the patella
QIAO Su-chi
XIAO Lei
LIU Chang
LI Cheng
WANG Zhi-wei
XU Wei-dong
Abstract：Objective To investigate the surgical treatment and clinical effects of in the treatment giant cell tumors of the patella. Methods A retrospective analysis of patients with giant cell tumors of the patella, treated at Department of Orthopedics in Changhai Hospital from February 2002 to June 2015, was conducted. Sixteen cases were screened according to the inclusion criteria and divided into two groups. Nine cases in the control group were treated with simple curettage and bone grafting, while 7 cases in the intervention group were treated with zoledronic acid before and after the operation. Changes before and after the surgery were compared. Bone healing time, functional recovery and incidence of adverse events were compared between the two groups. Results CT value, VAS score and knee circumference in the intervention group were significantly improved after the treatment ( P < 0.05 ). The average bone healing time of the intervention group was shorter than the control group ( P < 0.05 ). One and 3 months after the operation, HSS score of the intervention group was higher than that of the control group ( P < 0.05 ). Six months after the surgery, HSS scores of two groups were similar ( P > 0.05 ). No significant differences in postoperative recurrence rate existed between the 2 groups ( P > 0.05 ). Conclusions The use of curettage and bone grafting combined with zoledronic acid in treatment of giant cell tumors of the patellar has the benefits of improved clinical symptoms and signs, shorter bone healing time and better postoperative early functional recovery, with remarkable clinical effects.
Keywords：PatellaGiant cell tumor of the boneZoledronic acid
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 33-37 )