An experimental study on the relationship between the length/width ratio and survival rate of the axial pattern fascio-cutaneous flap and adipofascial flap
BI Zheng-gang
LI Qing-wei
YANG Cheng-lin
GENG Shuo
Abstract：Objective To explore the relationship between the length / width ratio and survival rate of the lfap with the rabbit axial pattern fascio-cutaneous lfap and adipofascial lfap as the experimental model.Methods Axial pattern faciocutaneous lfap and adipofascial lfap were created on both sides of the rabbit back with the thoracodorsal artery as the axial vessel. Fourteen rabbits were involved in the study with 28 lfaps, which were randomly divided into 4 groups based on the length / width ratio of the lfaps with 7 lfaps in each. Group A1: 4:1 axial patten fascio-cutaneous lfap. Group A2: 4:1 axial pattern adipofascial lfap. Group B1: 6:1 axial pattern fascio-cutaneous lfap. Group B2: 6:1 axial pattern adipofascial lfap. Following dissection the lfaps were sutured back in situ and survival condition was observed. Fifteen days after operation photos were taken and results were analyzed with Scion Image software to observe and record the survival of the individual lfaps. Statistical analysis was done. Micro-arterial angiography was done to demonstrate microcirculation in the lfaps.Results Fifteen days after operation the percentage of the survived portion of the lfaps was measured to ifnd a survival rate of ( 100±0.0 ) % in group A1 with well growth of new hair, a survival rate of 100% in Group A2 with infection in 1 lfap and obvious shrihkage in all lfaps, an averaged survival rate of ( 90.22±8.6 ) % in Group B1, and a survival rate of 100% in Group B2. The t test revealed that the survival rate of the lfaps in Group B1 was statistically lower with those in Group A and Group B2 witht=3.004,P=0.04. The micro-arterial angiography demonstrated the vascular pedicles of the lfaps were patent and the collateral circulation formed well after the operation.Conclusions At the length / width ratio of 6:1, both axial pattern fascio-cutaneous lfap and adipofascial lfap can survive safely in rabbits and axial adipofascial lfaps may have a higher survival rate than axial pattern fascio-cutaneous lfaps. Micro-arterial angiography can demonstrate the circulation status in lfaps intuitively, thus being an important procedure in lfap study.
Keywords：Surgical flapsMicrosurgeryAnimal experimentationSkin transplantationRabbits
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 451-455 )