Porous tricalcium phosphate for the repair of lacunar bone defects:afollow-upreport of 38 cases
XU Song-feng
XU Ming
YU Xiu-chun
SUN Yu-xi
YANG Yang
SU Qing
HU Rui
ZHAI Yong-fei
LU Jian-xi
Abstract：Objective To assess the over-2-year clinical outcomes of porous tricalcium phosphate ( TCP ) for the repair of lacunar bone defects. Methods A total of 38 patients with lacunar bone defects underwent the repair with porous TCP from March 2008 to September 2011, including 22 males and 16 females, whose average age was 23 years old ( range;3-58 years ). Tumor sizes varied from 0.72 cm3 to 151.88 cm3, with the average size of 35.62 cm3. All patients were followed up for a mean period of 41 months ( range;25-65 months ). The in vivo biodegradation rate of the implanted TCP was evaluated based on the radiographic analyzing method. The gray scale change of the grafting area in plain X-ray images was used to assess the degradation of porous TCP. Results There was neither signiifcant reverse reaction to the transplanted material nor locally inlfammatory reaction in all of the cases. Bone defects were repaired gradually, in company with the degradation of TCP materials and the formation of new bone. The rates of TCP degradation and new bone formation were fastest in the ifrst year postoperatively. The younger the patients were (<16 years old ) and the smaller the tumor size was (<10 cm3 ), the faster the rates were. Conclusions The porous TCP is an ideal material for the repair of lacunar bone defects caused by benign or invasive tumors, and the over-2-year follow-up results are satisfactory .
Keywords：Calcium phosphatesBone diseasesReconstructive surgical proceduresBiomedical research
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 282-286 )