Onset features and the treatment of spinal cord ischemia-reperfusion injury
AI Qi-yong
CAI Lin
LUO Yue
LIU Hui
HONG Guo-feng
Abstract：Objective To analyze and investigate the onset features and the treatment of spinal cord ischemia-reperfusion injury ( SCII ) based on the clinical data. Methods The clinical data of 6 patients with SCII who were adopted from January 2003 to September 2013 were retrospectively analyzed. Their mean age was ( 63±3.5 ) years old ( range;56-78 years ). SCII occurred to all the 6 patients within 2 hours after the operation. The data was collected, and the medical history characteristics, treatment and prognosis were objectively analyzed. Results The spinal cord dysfunction was gradually aggravated in the 6 patients at 1 to 2 hours after the spinal cord decompression surgery. All the patients were treated with large doses of methylprednisolone ( MP ), dehydration and neuronutritional medicine immediately. Thanks to the treatment, all of them were well recovered at 14 to 24 days after the surgery, and the normal spinal cord function was restored. Conclusions SCII mainly occurs in cervical and thoracic segments of the middle-aged and elderly patients. The degree of injury may be relevant to the anatomical and physiological characteristics, the degree, range and time of spinal cord compression and the perioperative treatment. The medical history, clinical symptoms and imaging data should be considered in the diagnosis. The MP is effective in the treatment of SCII .
Keywords：Spinal cord ischemiaReperfusion injuryDisease attributesTHERAPY
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 254-256 )