An analysis on the early clinical features of ankylosing spondylitis combined with the pain of knee
ZHANG Yong
ZHU Ming-sheng
YANG Lin
ZHANG Chong
MENG Wei-zheng
Abstract：objective To explore the early clinical featrures of ankylosing spondylitis ( AS ) combined with the knee acute pain as the ifrst symptom to improve the treatment.Methods From December 2009 to December 2012, there were 21 cases of ankylosing spondylitis combined with the ifrst symptom of acute pain of the knee joint. The early clinical features, imaging and laboratory parameters were recorded and retrospectively analyzed.Results The age of the patients was ranging from 17 to 45 years. The ifrst symptom of 21 patients was mainly knee acute pain. Knee joint effusion was yellow and turbid. Smear leucocyte under microscope was 4 +. Synovial tissue of the knee joint was inlfammatory granulation tissue. The erythrocyte sedimentation rate ( ESR ), C-reactive protein amount, and ifbrinogen amount were higher than the normal. 18 cases of HLA-B27 were positive. MRI of the knee joint showed that there were synovial proliferation and joint effusion. X-ray of sacroiliac joint and spine in 16 cases revealed that there were no obvious abnormal changes.Conclusions With unconspicuous onset, acute pain of the knee joint is always regarded as the ifrst symptom of ankylosing spondylitis. Missed and delayed diagnosis rate are high. Early screening for the knee symptoms of young patients, better understanding of history, careful examination and close observation of the disease are necessary to provide valuable information for the early disagnosis and prevention of ankylosing spondylitis.
Keywords：SpondylitisankylosingKnee jointArthralgia
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 35-37 )